1. SECOND CYCLE - MASTER'S DEGREE
  2. THE GRADUATE SCHOOL OF NATURAL AND APPLIED SCIENCES
  3. BIOLOGY DEPARTMENT
  4. 1741 Biology PhD
Course Information Course Learning Outcomes Course's Contribution To Program ECTS Workload Course Details
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COURSE INFORMATION
Course CodeCourse TitleL+P HourSemesterECTS
BIO 656COMPUTATIONAL METHODS FOR MOLECULAR BIOLOGICAL AND BIOTECHNOLOGICAL STUDIES3 + 02nd Semester7,5

COURSE DESCRIPTION
Course Level Master's Degree
Course Type Elective
Course Objective The aim of the course is to help make basic calculations that may be necessary for Molecular Biological and Biotechnological studies with correct approaches. With the theoretical and practical knowledge obtained at the end of the course, researchers are expected to learn the mathematical and statistical methods necessary to easily solve the basic problems they encounter in scientific studies and thus reach the most accurate result.
Course Content Scientific Notation and Metric Prefixes, Solutions, Mixtures and Media, Cell Growth: Working with Bacteriophage, Determining the Amount of Nucleic Acids, Labeling Nucleic Acids with Radioisotopes; Oligonucleotide Synthesis: Synthesis Yield; Polymerase Chain Reaction Activity; Measurement of Gene Expression by Real-Time PCR; Calculation of Relative Quantity by Reaction Kinetics in Real-Time PCR; Digital PCR; Recombinant DNA: Quantification of Fragment Ends; Use of β-Galactosidase to Monitor Promoter Activity and Gene Expression; Use of Luciferase in Reporter Analysis; Forensic Medicine and Paternity: Calculating Genotype Frequency.
Prerequisites No the prerequisite of lesson.
Corequisite No the corequisite of lesson.
Mode of Delivery Face to Face

COURSE LEARNING OUTCOMES
1Knowing and applying basic calculations used in molecular biology and biotechnology
2Being able to interpret the results obtained using the basic analysis methods used in molecular biology and biotechnology
3Being able to optimize the applications in molecular biology and biotechnology
4Learning how to put calculations into practice in research and professional fields
5being able to select, apply and interpret the necessary experimental application for the problems encountered
6Determination of amount of nucleic acid, determination of oligonucleotide synthesis efficiency and PCR activity in a polymerase chain reaction, determination of relative amount with reaction kinetics in real-time PCR
8Having detailed computational knowledge about recombinant DNA techniques
9having knowledge about the use and applications of molecular biological techniques in forensic sciences
7Having knowledge about digital PCR working principles and application fields

COURSE'S CONTRIBUTION TO PROGRAM
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ECTS ALLOCATED BASED ON STUDENT WORKLOAD BY THE COURSE DESCRIPTION
ActivitiesQuantityDuration (Hour)Total Work Load (Hour)
Course Duration (14 weeks/theoric+practical)14342
Hours for off-the-classroom study (Pre-study, practice)14798
Assignments155
Mid-terms11515
Final examination13535
Total Work Load

ECTS Credit of the Course





195

7,5
COURSE DETAILS
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L+P: Lecture and Practice
PQ: Program Learning Outcomes
LO: Course Learning Outcomes