PAÜ .:. Eğitim Öğretim Bilgi Sistemi

COURSE INFORMATION

Course Code	Course Title	L+P Hour	Semester	ECTS
FAR 502	EXPERIMENTATION AND TECHNIQUES IN LABORATORY ANIMALS	2 + 2	2nd Semester	5

COURSE DESCRIPTION

Course Level	Master's Degree
Course Type	Elective
Course Objective	Acquire therotical and practical knowledge of experimental animals and experimental methods
Course Content	Ethics in animal experiments Biology of rat Dissection procedures, Internal organs Skeletal muscles Brain and spinal cord: nuclei and regions Control methods, administration methods, Anesthesia, Drug Solution, Calculation of ED50/LD50 in pharmacological experiments vascular catheterization Stress and gastric ulcer induction methods Ovariectomy, Hysterectomy and hormones Isolated organs: Intestine or uterus Isolated organs: Heart or aorta
Prerequisites	No the prerequisite of lesson.
Corequisite	No the corequisite of lesson.
Mode of Delivery	Face to Face

COURSE LEARNING OUTCOMES

1	To understand and apply the ethics in experimental animals
2	To understand the rat biyology and to practice dissection methods
3	To understan and apply the control methods,anesthesia, drug administration routes,and calculation of ED50/ld50 in experimental animals
4	To understand and apply various disease models and isolated organ experiments in experimental animals.

COURSE'S CONTRIBUTION TO PROGRAM

	PO 01	PO 02	PO 03	PO 04	PO 05	PO 06	PO 07	PO 08
LO 001					5	5		5
LO 002		3			4	5		5
LO 003		5	4	5	5	5		5
LO 004	5	5	5	5	5	5	5	5
Sub Total	5	13	9	10	19	20	5	20
Contribution	1	3	2	3	5	5	1	5

ECTS ALLOCATED BASED ON STUDENT WORKLOAD BY THE COURSE DESCRIPTION

Activities	Quantity	Duration (Hour)	Total Work Load (Hour)
Course Duration (14 weeks/theoric+practical)	14	4	56
Hours for off-the-classroom study (Pre-study, practice)	1	10	10
Final examination	1	14	14
Midterm	1	20	20
Practice Professional Skills (Student)	2	15	30
Total Work Load ECTS Credit of the Course			130 5

COURSE DETAILS

Select Year

	Course Term	No	Instructors
Details	2019-2020 Fall	1	İZZETTİN HATİP

Course Details

Course Code	Course Title	L+P Hour	Course Code	Language Of Instruction	Course Semester
FAR 502	EXPERIMENTATION AND TECHNIQUES IN LABORATORY ANIMALS	2 + 2	1	Turkish	2019-2020 Fall

Course Coordinator	E-Mail	Phone Number	Course Location	Attendance
			TIP B0103 TIP C0107	%

Goals		Acquire therotical and practical knowledge of experimental animals and experimental methods
Content		Ethics in animal experiments Biology of rat Dissection procedures, Internal organs Skeletal muscles Brain and spinal cord: nuclei and regions Control methods, administration methods, Anesthesia, Drug Solution, Calculation of ED50/LD50 in pharmacological experiments vascular catheterization Stress and gastric ulcer induction methods Ovariectomy, Hysterectomy and hormones Isolated organs: Intestine or uterus Isolated organs: Heart or aorta

Topics

Weeks	Topics
1	Ethics in animal experiments
2	Biology of rat
3	Dissection procedures, internal organs
4	Skeletal muscles
5	Brain and spinal cord: nuclei and regions
6	Methods of experimental animals Control
7	Drug administration methods
8	Anesthesia in pharmacological experiments
9	Drug Solution
10	Calculation of ED50/LD50
11	Vascular catheterization
12	Stress and gastric ulcer induction methods
13	Ovariectomy, Hysterectomy and hormones
14	Isolated organs: Intestine or uterus Isolated organs: Heart or aorta

Materials

Materials are not specified.

Resources

Resources	Resources Language
Olds RJ, Olds JR. The Rat-Dissection guide. Wolf Medical Pub. LTD.London. 1991.	English
Institute of Laboratory Animal Resources. Guide fort he care and use of Laboratory Animals. National Academy Press. Washington DC. 1996.	English
Van Dongen JJ, Remie R. Manual of Microsurgery on theLaboratory Rat. Elsevier. Amsterdam. 1990.	English
The Staff of the Department of Pharmacology University of Edinburg. Pharmacological Experiments on intact preparations. Churchil, Livingstone. GB. 1975.	English
Cooley RK, Vanderwolf CH. Stereotaxic Surgery in the Rat: A Photographic series. AL Kirby Co. London. 1990.	English
Paxinos G., Watson C. The Rat Brain in Stereotaxic Coordinates. 2nd ed. Academic Pres INC. London1986.	English
Olds RJ, Olds JR. The Rat-Dissection guide. Wolf Medical Pub. LTD.London. 1991.	English
Institute of Laboratory Animal Resources. Guide fort he care and use of Laboratory Animals. National Academy Press. Washington DC. 1996.	English
Van Dongen JJ, Remie R. Manual of Microsurgery on theLaboratory Rat. Elsevier. Amsterdam. 1990.	English
The Staff of the Department of Pharmacology University of Edinburg. Pharmacological Experiments on intact preparations. Churchil, Livingstone. GB. 1975.	English
Cooley RK, Vanderwolf CH. Stereotaxic Surgery in the Rat: A Photographic series. AL Kirby Co. London. 1990.	English
Paxinos G., Watson C. The Rat Brain in Stereotaxic Coordinates. 2nd ed. Academic Pres INC. London1986.	English

Course Assessment

Assesment Methods	Percentage (%)	Assesment Methods Title
Final Exam	50	Final Exam
Midterm Exam	50	Midterm Exam

L+P: Lecture and Practice
PQ: Program Learning Outcomes
LO: Course Learning Outcomes

Prospective Student