PAÜ .:. Eğitim Öğretim Bilgi Sistemi

COURSE INFORMATION

Course Code	Course Title	L+P Hour	Semester	ECTS
NOB 714	MOLECULAR NEUROPHARMACOLOGY	2 + 0	1st Semester	7,5

COURSE DESCRIPTION

Course Level	Doctorate Degree
Course Type	Elective
Course Objective	Learning the neurochemical systems and structures which mediate to effect mechanisms of the drugs used for nervous system
Course Content	iBasic concepts of moleculer neuropharmacology Pharmacodynamic and pharmacokinetics of basic molecular and ultra structurals, receptors, postreceptor events, neuromediators. Serotonergic system, histamine, adenosine Dopaminergic system Noradrenegenic and adrenergic system Asetilcolin and colinergic system, neurochemistry of learning and memory Aminoacid transmitters,glutamete excitotoxicity; endothelins and nitric oxide; endogenous cannabinoid system, opioid system Neuroactive peptides, neurotrophic factors Molecular mechanisms and related neuromediators of epilepsy Neuropharmacology of motor and extrapyramidal system Molecular mechanism of cerebral ischemic processes Molecular mechanism of degenerative processes Pain mechanisms and related mediators Neuropharmocology of sleep and vestibular system
Prerequisites	No the prerequisite of lesson.
Corequisite	No the corequisite of lesson.
Mode of Delivery	Face to Face

COURSE LEARNING OUTCOMES

1	Understanding the ultra and chemical structurals of nervous system.
2	To learn the elements and structures that mediate drug mechanisms which affect nervous system.
3	Learning the neuromediators which is functional on nervous system, related system and pathways.
4	Learning the neurochemical state, effected molecular mechanisms, pathological substrats in nervous system disorders.

COURSE'S CONTRIBUTION TO PROGRAM

	PO 01	PO 02	PO 03	PO 04	PO 05	PO 06	PO 07	PO 08	PO 09	PO 10	PO 11
LO 001	5	3	5	2	5
LO 002	2	5	4	3			3		2	5	3
LO 003		5	3			2	3	5
LO 004	5	5	5	3	2	4	3	3	2	3	4
Sub Total	12	18	17	8	7	6	9	8	4	8	7
Contribution	3	5	4	2	2	2	2	2	1	2	2

ECTS ALLOCATED BASED ON STUDENT WORKLOAD BY THE COURSE DESCRIPTION

Activities	Quantity	Duration (Hour)	Total Work Load (Hour)
Course Duration (14 weeks/theoric+practical)	14	2	28
Hours for off-the-classroom study (Pre-study, practice)	14	8	112
Mid-terms	1	15	15
Final examination	1	20	20
Division Academic Activity	1	5	5
Division Academic Activity (Student)	1	15	15
Total Work Load ECTS Credit of the Course			195 7,5

COURSE DETAILS

Select Year

	Course Term	No	Instructors
Details	2016-2017 Spring	1	LEVENT SİNAN BİR
Details	2016-2017 Fall	1	LEVENT SİNAN BİR

Course Details

Course Code	Course Title	L+P Hour	Course Code	Language Of Instruction	Course Semester
NOB 714	MOLECULAR NEUROPHARMACOLOGY	2 + 0	1	Turkish	2016-2017 Spring

Course Coordinator	E-Mail	Phone Number	Course Location	Attendance
Prof. Dr. LEVENT SİNAN BİR	sbir@pau.edu.tr		TIP D0110	%

Goals		Learning the neurochemical systems and structures which mediate to effect mechanisms of the drugs used for nervous system
Content		iBasic concepts of moleculer neuropharmacology Pharmacodynamic and pharmacokinetics of basic molecular and ultra structurals, receptors, postreceptor events, neuromediators. Serotonergic system, histamine, adenosine Dopaminergic system Noradrenegenic and adrenergic system Asetilcolin and colinergic system, neurochemistry of learning and memory Aminoacid transmitters,glutamete excitotoxicity; endothelins and nitric oxide; endogenous cannabinoid system, opioid system Neuroactive peptides, neurotrophic factors Molecular mechanisms and related neuromediators of epilepsy Neuropharmacology of motor and extrapyramidal system Molecular mechanism of cerebral ischemic processes Molecular mechanism of degenerative processes Pain mechanisms and related mediators Neuropharmocology of sleep and vestibular system

Topics

Weeks	Topics
1	Basic concepts of moleculer neuropharmacology
2	Basic molecular and ultra structural elements which play role in pharmacodynamy and pharmacokinetics; neuromediators, receptors and postreceptor events,
3	Serotonergic system, histamine, adenosine
4	Dopaminergic system
5	Noradrenegenic and adrenergic system
6	Asetilcolin and colinergic system, neurochemistry of learning and memory
7	Aminoacid transmitters,glutamete excitotoxicity; endothelins and nitric oxide; endogenous cannabinoid system, opioid system
8	Neuroactive peptides, neurotrophic factors
9	Molecular mechanisms and related neuromediators of epilepsy
10	Molecular mechanism of cerebral ischemic processes
11	Molecular mechanism of degenerative processes
12	Pain mechanisms and related mediators
13	Neuropharmacology of motor and extrapyramidal system
14	Neuropharmocology of sleep and vestibular system

Materials

Materials are not specified.

Resources

Resources	Resources Language
Cooper JR, Bloom FE, Roth RH (eds) The biochemical basis of Neuropharmacology. 8th ed. Oxford University Press 2003	English
Bir LS (ed) Türkiye Klinikleri Dergisi Nörofarmakoloji Özel Sayısı, 2010	Türkçe
Cooper JR, Bloom FE, Roth RH (eds) The biochemical basis of Neuropharmacology. 8th ed. Oxford University Press 2003	English
Bir LS (ed) Türkiye Klinikleri Dergisi Nörofarmakoloji Özel Sayısı, 2010	Türkçe

Course Assessment

Assesment Methods	Percentage (%)	Assesment Methods Title
Final Exam	50	Final Exam
Midterm Exam	50	Midterm Exam

L+P: Lecture and Practice
PQ: Program Learning Outcomes
LO: Course Learning Outcomes

Prospective Student