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COURSE INFORMATION
Course CodeCourse TitleL+P HourSemesterECTS
BIY 310MOLECULAR BIOLOGY OF GENE3 + 06th Semester4

COURSE DESCRIPTION
Course Level Bachelor's Degree
Course Type Compulsory
Course Objective The study of Molecular Gene Biology (MGB) is one of the most rapidly advancing and exciting areas in biology. Advancements in the areas of cloning, gene splicing and gene expression are covered during the course . MGB is the study of the function and structure of genes, and how they regulate the growth and the specialization of living cells. It is the basic science for study for those who want to work in the exciting new biotechnology industries.
Course Content Definition of macro molecule: types of nucleic acids, their function, their chemical structure, macro molecular structure of DNA, chromatin, macro molecular structure of RNA. Control mechanism of DNA and repaired mechanism of DNA: control of gene expression, gene regulation during development, developmental genetics: cell fate and pattern formation., Xerodermo pigmentosum. Cancer: cell cycle regulation and genetic of cancer. Retroviruses:what are the retroviruses? Why are they important? Prions: What are prions? Why are they important? Are they genetically important? Transposable genetic elements: insertion sequences, transposons, mechanism of transpostion, Rewiew of tranposable element in prokaryotes, Ty elemens in yeast, transposable element in Drosophila, transposition via an RNA intermediate, controlling elements in maize review of transposable elements in eukaryote. Why they are important for living organism? Gene therapy: What is gene therapy? How is it done? Somatic gene therapy and germ line gene therapy. What is the advantages and disadvantages of gene therapy for human. Social and ethical problems. Recombinant DNA technology: application of recombinant technology in human life.
Prerequisites No the prerequisite of lesson.
Corequisite No the corequisite of lesson.
Mode of Delivery Face to Face

COURSE LEARNING OUTCOMES
1Will be able to know definition of macro molecule.
2Will be able to know control mechanism of DNA and repaired mechanism of DNA.
3Will be able to know cell cycle regulation and genetic of cancer.
4Determines the working methods of retroviruses.
5Transmits information about prions.
6Gives current information about the transfer of recombinant DNA technology.

COURSE'S CONTRIBUTION TO PROGRAM
PO 01PO 02PO 03PO 04PO 05PO 06PO 07PO 08PO 09PO 10PO 11PO 12
LO 001            
LO 0023 34   4 334
LO 003            
LO 004            
LO 0052345445     
LO 006            
Sub Total53794454 334
Contribution111211110111

ECTS ALLOCATED BASED ON STUDENT WORKLOAD BY THE COURSE DESCRIPTION
ActivitiesQuantityDuration (Hour)Total Work Load (Hour)
Course Duration (14 weeks/theoric+practical)13339
Hours for off-the-classroom study (Pre-study, practice)13226
Mid-terms11313
Final examination12626
Total Work Load

ECTS Credit of the Course






104

4
COURSE DETAILS
 Select Year   


 Course TermNoInstructors
Details 2023-2024 Spring1ALİ RAMAZAN ALAN
Details 2022-2023 Spring1ALİ RAMAZAN ALAN
Details 2021-2022 Spring1ALİ RAMAZAN ALAN
Details 2020-2021 Spring1ALİ RAMAZAN ALAN
Details 2019-2020 Spring1ALİ RAMAZAN ALAN
Details 2018-2019 Spring1ALİ RAMAZAN ALAN
Details 2017-2018 Spring1ALİ RAMAZAN ALAN
Details 2016-2017 Spring1ALİ RAMAZAN ALAN
Details 2015-2016 Spring1ALİ RAMAZAN ALAN
Details 2014-2015 Spring1FEVZİYE ÇELEBİ TOPRAK
Details 2014-2015 Spring2ALİ RAMAZAN ALAN
Details 2013-2014 Spring1FEVZİYE ÇELEBİ TOPRAK
Details 2013-2014 Spring2ALİ RAMAZAN ALAN
Details 2012-2013 Spring1FEVZİYE ÇELEBİ TOPRAK
Details 2012-2013 Spring2ALİ RAMAZAN ALAN
Details 2011-2012 Spring1FEVZİYE ÇELEBİ TOPRAK
Details 2011-2012 Spring2FEVZİYE ÇELEBİ TOPRAK
Details 2010-2011 Spring1HAKAN AKÇA
Details 2010-2011 Spring2HAKAN AKÇA


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Course Details
Course Code Course Title L+P Hour Course Code Language Of Instruction Course Semester
BIY 310 MOLECULAR BIOLOGY OF GENE 3 + 0 1 Turkish 2023-2024 Spring
Course Coordinator  E-Mail  Phone Number  Course Location Attendance
Prof. Dr. ALİ RAMAZAN ALAN aalan@pau.edu.tr FEN B0112 %80
Goals The study of Molecular Gene Biology (MGB) is one of the most rapidly advancing and exciting areas in biology. Advancements in the areas of cloning, gene splicing and gene expression are covered during the course . MGB is the study of the function and structure of genes, and how they regulate the growth and the specialization of living cells. It is the basic science for study for those who want to work in the exciting new biotechnology industries.
Content Definition of macro molecule: types of nucleic acids, their function, their chemical structure, macro molecular structure of DNA, chromatin, macro molecular structure of RNA. Control mechanism of DNA and repaired mechanism of DNA: control of gene expression, gene regulation during development, developmental genetics: cell fate and pattern formation., Xerodermo pigmentosum. Cancer: cell cycle regulation and genetic of cancer. Retroviruses:what are the retroviruses? Why are they important? Prions: What are prions? Why are they important? Are they genetically important? Transposable genetic elements: insertion sequences, transposons, mechanism of transpostion, Rewiew of tranposable element in prokaryotes, Ty elemens in yeast, transposable element in Drosophila, transposition via an RNA intermediate, controlling elements in maize review of transposable elements in eukaryote. Why they are important for living organism? Gene therapy: What is gene therapy? How is it done? Somatic gene therapy and germ line gene therapy. What is the advantages and disadvantages of gene therapy for human. Social and ethical problems. Recombinant DNA technology: application of recombinant technology in human life.
Topics
WeeksTopics
1 MACROMOLECULAR STRUCTURE
2 DNA REPLICATION
3 TRANSCRIPTION
4 TRANSLATION
5 DNA REPAIR MECHANISM
6 DNA REPAIR MECHANISM
7 REGULATION OF PROTEIN SYNTHESIS
8 CELL PROCESSING IS REGULATED BY ENZYMES
9 TRANSPOSABLE ELEMENTS
10 RETROVIRUSES
11 PRIONS and VIROIDS
12 CANCER
13 GENETICAL CONTROL OF MORPHOGENESIS
14 RECOMBINANT DNA TECHNOLOGY
Materials
Materials are not specified.
Resources
Course Assessment
Assesment MethodsPercentage (%)Assesment Methods Title
Final Exam60Final Exam
Midterm Exam40Midterm Exam
L+P: Lecture and Practice
PQ: Program Learning Outcomes
LO: Course Learning Outcomes