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COURSE INFORMATION
Course CodeCourse TitleL+P HourSemesterECTS
BIY 305GENETICS3 + 05th Semester4

COURSE DESCRIPTION
Course Level Bachelor's Degree
Course Type Compulsory
Course Objective The study of genetics is one of the most rapidly advancing and exciting areas in biology and medicine today. During the course, students learn fundamental principles of eukaryotic and prokaryotic genetics. The course discusses studies of Mendel and how Mendelian genetics can be used in genetic analysis of human genetic diseases. During the course, extensions to Mendelian genetics, gene linkage, and recombination is covered in detail. At the end of the course, students will be able to analyze problems related to the field of genetics based on their course training.
Course Content Introduction of Genetics: History and historical development of genetics, Chromosome theory of inheritance: genetic material, gen and chromosome, cell cycle (mitosis ve meiosis), chromosomes theory of heredity and problem solving with the related topics. Mendel Genetics: Mendel Laws, chi-square test and pedigree Extensions of Mendelian Analysis:Variation on dominance (codominance and incomplete dominance), various genes affecting the same character (epistasi), pleitropi, multiple alleles, lethal alleles, sex chromosomes and sex linkage, sex limited inheritance and environmental effect on genetics Linkage:The discovery of linkage, recombination, linkage maps, three-point test cross, interference, examples of linkage maps, nature of crossing-over. Tetrad analysis, mitotic recombination and segregation. The structure of DNA: DNA genetic material, the structure of DNA, replication of DNA, mechanism of DNA replication, DNA replication in eukaryotes, DNA and gene. DNA function:Transcription, translation, genetik code, protein synthesis, universality of genetic information transfer, eukaryotic RNA, and mechanism of gene splicing. Control of gene expression:Prokaryotic gene expression, discovery of Lac operon (positive and negative control), and problem solving. Recombination in bacteria and their viruses: transfer mechanisms in bacteria: bacterial conjugation, bacterial recombination and mapping the E. coli chromosome, bacterial transformation, bacteriophage genetics, transduction, chromosome mapping, and bacterial gene transfer. The extranuclear genome:extranuclear inheritance in higher plants, extranuclear inheritance in fungi, shell coiling in snails, extranuclear gene in Chlamydomonas, mithochondrial genome, and chloroplast genome.
Prerequisites No the prerequisite of lesson.
Corequisite No the corequisite of lesson.
Mode of Delivery Face to Face

COURSE LEARNING OUTCOMES
6What is the the extranuclear genome? Students will be able to solve the problems about this topic.
5How to study of recombination in bacteria and their viruses? Students wil be able to solve the related problems of this topic.
1Will be able to know historical development of genetics.
2Will be able to know chromosome theory of inheritance (genetic material, gen and chromosome, cell cycle (mitosis ve meiosis), chromosomes theory of heredity and problem solving with the related topics).
3Will be able to know Mendel laws and extensions of Mendelian analysis.
4Will be able to know the structure and function of DNA.

COURSE'S CONTRIBUTION TO PROGRAM
PO 01PO 02PO 03PO 04PO 05PO 06PO 07PO 08PO 09PO 10PO 11PO 12
LO 0015 54   5    
LO 0025           
LO 0035           
LO 0045           
LO 005 55         
LO 0065  4        
Sub Total255108   5    
Contribution412100010000

ECTS ALLOCATED BASED ON STUDENT WORKLOAD BY THE COURSE DESCRIPTION
ActivitiesQuantityDuration (Hour)Total Work Load (Hour)
Course Duration (14 weeks/theoric+practical)13339
Hours for off-the-classroom study (Pre-study, practice)13226
Mid-terms11313
Final examination12626
Total Work Load

ECTS Credit of the Course






104

4
COURSE DETAILS
 Select Year   


 Course TermNoInstructors
Details 2020-2021 Fall1ALİ RAMAZAN ALAN


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Course Details
Course Code Course Title L+P Hour Course Code Language Of Instruction Course Semester
BIY 305 GENETICS 3 + 0 1 Turkish 2020-2021 Fall
Course Coordinator  E-Mail  Phone Number  Course Location Attendance
Prof. Dr. ALİ RAMAZAN ALAN aalan@pau.edu.tr FEN B0112 %80
Goals The study of genetics is one of the most rapidly advancing and exciting areas in biology and medicine today. During the course, students learn fundamental principles of eukaryotic and prokaryotic genetics. The course discusses studies of Mendel and how Mendelian genetics can be used in genetic analysis of human genetic diseases. During the course, extensions to Mendelian genetics, gene linkage, and recombination is covered in detail. At the end of the course, students will be able to analyze problems related to the field of genetics based on their course training.
Content Introduction of Genetics: History and historical development of genetics, Chromosome theory of inheritance: genetic material, gen and chromosome, cell cycle (mitosis ve meiosis), chromosomes theory of heredity and problem solving with the related topics. Mendel Genetics: Mendel Laws, chi-square test and pedigree Extensions of Mendelian Analysis:Variation on dominance (codominance and incomplete dominance), various genes affecting the same character (epistasi), pleitropi, multiple alleles, lethal alleles, sex chromosomes and sex linkage, sex limited inheritance and environmental effect on genetics Linkage:The discovery of linkage, recombination, linkage maps, three-point test cross, interference, examples of linkage maps, nature of crossing-over. Tetrad analysis, mitotic recombination and segregation. The structure of DNA: DNA genetic material, the structure of DNA, replication of DNA, mechanism of DNA replication, DNA replication in eukaryotes, DNA and gene. DNA function:Transcription, translation, genetik code, protein synthesis, universality of genetic information transfer, eukaryotic RNA, and mechanism of gene splicing. Control of gene expression:Prokaryotic gene expression, discovery of Lac operon (positive and negative control), and problem solving. Recombination in bacteria and their viruses: transfer mechanisms in bacteria: bacterial conjugation, bacterial recombination and mapping the E. coli chromosome, bacterial transformation, bacteriophage genetics, transduction, chromosome mapping, and bacterial gene transfer. The extranuclear genome:extranuclear inheritance in higher plants, extranuclear inheritance in fungi, shell coiling in snails, extranuclear gene in Chlamydomonas, mithochondrial genome, and chloroplast genome.
Topics
WeeksTopics
1 Introduction to Genetics
2 Genetic mutations
3 Genetics of bacteria and viruses (I)
4 Genetics of bacteria and viruses (II)
5 Genetics of bacteria and viruses (III)
6 Prokaryotic gene regulation
7 The chromosomal basis of inheritance
8 Patterns of inheritance (I)
9 Patterns of inheritance (II)
10 Large-scale chromosomal changes
11 Interaction of genes
12 Eukaryotic chromosome mapping (I)
13 Eukaryotic chromosome mapping (II)
14 Eukaryotic chromosome mapping (III)
Materials
Materials are not specified.
Resources
ResourcesResources Language
Genetik Kavramlar (Klug ve ark. )(8. Baskıdan Çeviri)Türkçe
Introduction to Genetic Analysis (Griffiths et al.)English
Course Assessment
Assesment MethodsPercentage (%)Assesment Methods Title
Final Exam60Final Exam
Midterm Exam40Midterm Exam
L+P: Lecture and Practice
PQ: Program Learning Outcomes
LO: Course Learning Outcomes